Combination of Liver Extract and Folic Acid

The question was originally raised on the basis of a pointer in the ' Current Therapy', 1949. This appeared to be very significant in view of the prevailing tendency to combine anti-anaemic substances irrespective of a consideration of rationality and/or therapeutic efficacy. The inferences of your correspondent are interesting and apparently have been drawn from a different angle. There is another side of the picture that cannot possibly be ignored. The combination has been disfavoured from the point of view of rationale and clinical response. -To support, I quote below a few lines from a communication to me by the commentator in the ' Current Therapy' Dr. Frank H. Bethell, Professor of Internal Medicine and Assistant Director, Thomas Henry Simpson Memorial Institute for Medical Research, University of Michigan, Ann Arbor, Michigan (U.S.A.). ' Folic acid is a relatively simple chemical compound ordinarily quite well absorbed from the gastro-intestinal tract.